Assess Each and every individual’s possibility previous to prescribing and watch consistently for the development of such disorders
C: Use with caution if Advantages outweigh pitfalls. Animal scientific studies present danger and human reports not obtainable or neither animal nor human scientific studies done.
Simply call a Health care service provider without delay if you have any of these indications, especially if These are new, even worse, or be concerned you:
stiripentol will lessen the extent or effect of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Carefully. Contemplate lessening the dose of CYP2C19 substrates, if adverse reactions are seasoned when administered concomitantly with stiripentol.
quinupristin/dalfopristin will increase the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
diazepam raises toxicity of oliceridine by Other get more info (see comment). Modify Therapy/Monitor Carefully. Comment: Anticholinergic drugs may perhaps increase risk of urinary retention and/or serious constipation, which may produce paralytic ileus.
rifapentine will reduce the level or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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sage decreases outcomes of diazepam by pharmacodynamic antagonism. Slight/Importance Mysterious. Theoretical interaction; some species of sage may induce convulsions.
Dihydrocodeine belongs to a gaggle of medicines termed opioids. It works by blocking discomfort indicators with the central nervous system and also the Mind.
etravirine will lower the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Propylene glycol toxicity reported in patients treated with diazepam injection at doses drastically greater than advised when it was getting used to deal with Liquor withdrawal signs and symptoms at doses >900 mg/day Propylene glycol toxicity is associated with an anion hole metabolic acidosis, serum hyperosmolality, and amplified lactate
diazepam improves toxicity of oliceridine by Other (see comment). Modify Therapy/Monitor Carefully. Remark: Anticholinergic medications could improve threat of urinary retention and/or severe constipation, which may bring on paralytic ileus.